Melanotan II (MT2) is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH), naturally involved in regulating pigmentation and energy balance in the body. As one of the most widely studied compounds in melanocortin research, it has demonstrated a strong ability to activate melanocortin receptors across multiple systems, making it a cornerstone compound in pigmentation, appetite, and neuroendocrine research.
Mechanism
MT2 acts as a non-selective agonist at melanocortin receptors MC1R, MC3R, MC4R, and MC5R. Activation of MC1R drives melanogenesis in melanocytes, while MC3R and MC4R engagement influences appetite regulation, energy expenditure, and central nervous system signaling. It has also been studied for effects on sexual arousal pathways and inflammatory response.
Research Areas: Pigmentation & melanogenesis · Appetite & metabolic regulation · Melanocortin receptor pharmacology · Neuroendocrine signaling · Sexual function research · Inflammation modulation
For research use only. Not for human consumption.
